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Table 5 Comparison of the present results with those from other studies involving TFR indication for TFR: tumor disease, failed arthroplasty or both (= mixed)

From: Is total femoral replacement for non-oncologic and oncologic indications a safe procedure in limb preservation surgery? A single center experience of 22 cases

Authors Number of patients Follow-up (months) Average age (years) Indication for TFR MSTS score (%) Revision-rate (%) Survivorship of TFR Complications requiring surgery (no. patients)
Puri [11] 5/8 33 32 Tumor 80 12.5 88% Infection (1)
Ruggieri [16] 21/23 48 21 Tumor 66 23.8 One failure Infection (2), mechanical failure (3)
Kalra [8] 11/26 57 40 Tumor 72 11.5 80% prosthetic survival at 10 years Loosening (1), dislocation (3), deep infection (2), foot drop (1), amputation (2)
Natarajan [9] 17/17 54 31 Tumor 67 23.5 82.4% Infections (2), Hip dislocations (2)
Ahmed [3] 4/9 51 47 Tumor 72 33 66% Infection (2), tibial component lossening (1)
Amanatullah [14] 20 73 65 Failed arthroplasty NA 30 70% at 5 years Infection (7), hip dislocation (5), limb length discrepancy (2), knee flexion contracture (1)
Berend [4] 58/59 58 74 Failed arthroplasty NA 30.5 65% at 5 years Infection (8), hip dislocation (7), tibial component loosening (2), acetabular component loosening (1)
Fontain [6] 12/14 90 63 Failed arthroplasty 59 35.7 NA Hip dislocation (5), infection (3)
Friesecke [7] 81/100 59 68 Failed arthroplasty 77 21 NA Infection (12), hip dislocation (6), prosthesis failure (3), patellar issues (2), hematoma (2), peroneal nerve palsy (1), delayed wound healing (1)
Lombardi [1] 50/75 42 73 Failed arthroplasty NA 30.7 NA Infection (11), hip dislocation (7), tibial component loosening (2), acetabular component loosening (1), hematoma (1), periprosthetic fracture (1)
Mankin [15] 15 54 52 Mixed NA 33.3 NA Prosthesis failure (4), infection (1)
Nerubay [17] 7/19 18–96 20 Tumor NA NA NA Wound healing problems (10), infection (1), popliteal vein injury (1), prosthesis failure (1)
Steinbrink [18] 32 6–84 56 Mixed NA 9.4 NA Infection (2), hip dislocation (1), prosthesis failure (1), patellar pain (1)
Ward [16] 11/21 31 44.6 Mixed NA 2.4 NA Infection (3), hip dislocation (2), patellar pain (1)
Current study 22/36 63 66 Mixed 43 59.1 81.8% at 5 years Infection (5), hip dislocation (2), wound healing problems (5), prosthesis failure (2), arthrofibrosis (2)
  1. Number of patients (x/y): number of patients included in study/total number of patients including drop-outs