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|
Factor
|
Category
|
Multivariable analysis
|
|---|
|
Localized, regional
|
Distant
|
|---|
|
HR
|
95% CI
|
P value
|
HR
|
95% CI
|
P value
|
|---|
|
Age
| |
1.724
|
0.969–3.068
|
0.064
|
2.765
|
1.572–4.866
|
0.000
|
|
Race
|
White
| | |
0.095
| | |
0.370
|
|
Black
|
1.526
|
0.721–3.229
|
0.269
|
1.635
|
0.809–3.306
|
0.171
|
|
Other
|
0.502
|
0.219–1.148
|
0.102
|
0.947
|
0.425–2.109
|
0.895
|
|
Histological grade
|
I
| | |
0.920
| | | |
|
II
|
0.000
|
0.000–4.851E+56
|
0.888
| | |
0.343
|
|
III
|
3.210
|
0.276–37.364
|
0.352
|
0.172
|
0.017–1.728
|
0.135
|
|
IV
|
2.863
|
0.249–32.961
|
0.399
|
0.183
|
0.018–1.868
|
0.152
|
|
Unknown
|
2.422
|
0.241–24.342
|
0.452
|
0.139
|
0.015–1.307
|
0.084
|
|
TNM stage
|
I
| | |
0.180
| | | |
|
II
|
0.000
|
0.000–1.832E+56
|
0.877
| | | |
|
III
|
0.000
|
0.000–3.701E+55
|
0.859
| | | |
|
IV
|
0.000
|
0.000–8.405E+55
|
0.868
| | | |
|
Unknown
|
0.000
|
0.000–4.593E+55
|
0.862
|
2.810
|
0.823–9.595
|
0.099
|
|
Tumour size
|
< 3 cm
| | |
0.112
| | |
0.102
|
|
3 cm–5 cm
|
2.356
|
0.597–9.301
|
0.221
|
0.677
|
0.110–4.182
|
0.675
|
|
> 5 cm
|
5.128
|
1.252–21.004
|
0.023
|
1.180
|
0.231–6.035
|
0.843
|
|
Unknown
|
4.278
|
1.060–17.265
|
0.041
|
1.998
|
0.345–11.588
|
0.440
|
|
LN metastases
|
No
| | | | | |
0.898
|
|
Yes
| | | |
1.224
|
0.435–3.444
|
0.702
|
|
Unknown
|
0.160
|
0.019–1.318
|
0.088
|
1.223
|
0.377–3.967
|
0.738
|
|
Distant metastases
|
No
| | | | | | |
|
Yes
| | | | | | |
|
Unknown
|
11.736
|
1.292–106.592
|
0.029
| | | |
|
Radiation
|
Yes/no, unknown
|
2.319
|
1.148–4.682
|
0.019
|
1.432
|
0.790–2.595
|
0.237
|
|
Surgery
|
Yes/no, unknown
|
2.063
|
1.071–3.973
|
0.030
|
1.203
|
0.667–2.172
|
0.539
|
