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Pregnancy and perinatal postnatal outcome
|
Study (n)
|
Number of reports
|
Pregnancies or neonate (n)
|
Pooled % (95%–CI)
|
|---|
|
Pregnancy outcome
|
|
PTB < 34 week
|
25
|
68
|
719
|
9.5% [7.1–39.5]
|
|
PTB < 37 week
|
22
|
91
|
637
|
14.3% [10.2–30.2]
|
|
> 37 week
|
25
|
330
|
709
|
46.5% [41.2–56.3]
|
|
Pre-eclampsia
|
9
|
10
|
169
|
5.9% [3.6–11.7]
|
|
pPROM
|
11
|
17
|
183
|
9.3% [6.6–14.8]
|
|
FGR
|
14
|
3
|
108
|
2.8% [1.8–8.9]
|
|
Miscarriage
|
4
|
9
|
62
|
14.5% [7.7–26.5]
|
|
ICU admission
|
29
|
66
|
211
|
31.3% [27.2–55.5]
|
|
Maternal death
|
11
|
15
|
557
|
2.7% [1.4–14.6]
|
|
Cesarean delivery
|
32
|
440
|
772
|
56.9% [48.2–78.9]
|
|
Normal delivery
|
17
|
198
|
692
|
28.6% [22.4–41.6]
|
|
Prenatal outcome
|
|
Fetal distress
|
17
|
18
|
68
|
26.5% [17.5–39.5]
|
|
Apgar score < 7
|
16
|
1
|
81
|
1.2% [0.0–7.7]
|
|
Neonatal asphyxia
|
11
|
1
|
71
|
1.4% [0.0–8.9]
|
|
Admission to NICU
|
8
|
9
|
73
|
11.3% [5.6–20.3]
|
|
Perinatal death
|
21
|
10
|
452
|
2.2% [1.2–12.8]
|
|
Vertical transmission
|
39
|
0
|
1316
|
0.0% [0.0–1.0]
|
|
Coexisting disorders
|
|
Hypertension
|
7
|
81
|
954
|
8.5% [7.1–17.4]
|
|
Gestational diabetes
|
9
|
85
|
881
|
9.6% [6.6–20.7]
|
|
Cardiovascular disease
|
2
|
27
|
470
|
5.7% [3.0–12.1]
|
|
Digestive disease
|
3
|
4
|
111
|
3.6% [1.1–9.8]
|
|
Asthma
|
4
|
44
|
794
|
5.5% [2.3–36.4]
|
- PTB preterm birth, pPROM preterm premature rupture of membranes, FGR fetal growth restriction, ICU intensive care unit, NICU neonatal intensive care unit
